Evaluation of Flavonoid, Anthocynin, Tartaic Ester, Antifungal and Antibacterial Activity of Various Polar and Nonpolar Solvent Extract of Ayurvedic Drug
S. G. Funde
Abstract
This study is planned to determine the phytochemicals evaluation and antimicrobial activity of different solvent extracts of the prevalent plant Acorus calamus. Maximum polyphenolics compound get extracted in dimethyl sulphoxide, acetone, ethanol and methanol extracts where as high amount of anthocynins, flavonol and tartaric ester extraction in dimethyl sulphoxide, ethyl acetate and acetone and alcoholic extracts. Extraction of proanthocyanidins contents is observed in methanol and ethanol solvent extract as compare to other solvent extracts. The Acorus calamus was evaluated for its antimicrobial activity using a disk diffusion assay of methanol, ethanol, actone, ethyl acetate, actonitrril, trichloromethane, dichloromethane, water, tolune, bezene, hexane, dimethyl sulphoxide extracts resulting in the inhibition of a number of bacteria. It was found that all extracts showed pronounced inhibition on gram positive and Gram negative bacteria and fungus strains like B.subtilis, Ecoli and Aspergillus niger. The antimicrobial activities increased with increasing respective extracts concentration, but did not differentiate significantly in terms of the effect of extraction solvents. When various, pronounced antimicrobial activity on gram positive bacteria methanol, ethanol, actone, ethyl acetate, actonitrril, tri chloromethane, dichloromethane, water, tolune, bezene, hexane, dimethyl sulphoxide extracts suggest that maximum antibacterial activity was found for ethanol, methanol, ethyl acetate and dimethyl sulphoxide extracts. Where as high antifungal inhibition observed for ethanol, acetone, acetonitril extracts.
