Pages: 11-17

Abstract

C. trachomatis is one of the most common cause of STDs such as urethritis in men and cervicitis in women. Many of the infected adolescents and young adults are reported as asymptomatic reservoirs of C. trachomatis and are unaware of their infections. The untreated cervicitis infections of C. trachomatis cause many reproductive complications including PID, increasing chance of the development of cervical neoplasia, rupture of the membranes in pregnancy and chorioamnionitis. In this study the prevalence of C. trachomatis in FVU specimens of women with cervical infections and their IgM titers were investigated by PCR and serology, respectively. This study was conducted from May to September 2015 at teaching hospital of Razi, Ahvaz, Iran. In this study, from each woman participants one FVU sample and one blood sample was provided and overall 163 FVU and blood samples were collected from sexually active women (15-45 years) who had the symptomatic genital infections. Detection of C. trachomatis DNA was performed in FVU samples by PCR. Also, anti_C. trachomatis IgM antibody in the serum samples were recognized. Out of 163 FVU samples, 41(25.1%) cases were positive based on PCR technique. The anti C. trachomatis IgM was detected in 46 (28.2%) cases. In this study, there was a clear association between C. trachomatis infections with abortion, post coital bleeding and dyspareunia. Also, it seems both PCR and serology methods are appropriate for diagnosis of C. trachomatis infections.