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specialty journal of biological sciences
Volume 6, 2020, Issue 1
Evaluation of Flavonoid, Anthocynin, Tartaic Ester, Antifungal and Antibacterial Activity of Various ‎Polar and Nonpolar Solvent Extract of Ayurvedic Drug‎
S. G. Funde
Pages: 20-24

Abstract

This study is planned to determine the phytochemicals evaluation and antimicrobial activity of ‎different solvent extracts of the prevalent plant Acorus calamus. Maximum polyphenolics compound get ‎extracted in dimethyl sulphoxide, acetone, ethanol and methanol extracts where as high amount of ‎anthocynins, flavonol and tartaric ester extraction in dimethyl sulphoxide, ethyl acetate and acetone and ‎alcoholic extracts. Extraction of proanthocyanidins contents is observed in methanol and ethanol solvent ‎extract as compare to other solvent extracts. The Acorus calamus was evaluated for its antimicrobial ‎activity using a disk diffusion assay of methanol, ethanol, actone, ethyl acetate, actonitrril, trichloromethane, dichloromethane, water, tolune, bezene, hexane, dimethyl sulphoxide extracts resulting in ‎the inhibition of a number of bacteria. It was found that all extracts showed pronounced inhibition on gram ‎positive and Gram negative bacteria and fungus strains like B.subtilis, Ecoli and Aspergillus niger. The ‎antimicrobial activities increased with increasing respective extracts concentration, but did not ‎differentiate significantly in terms of the effect of extraction solvents. When various, pronounced ‎antimicrobial activity on gram positive bacteria methanol, ethanol, actone, ethyl acetate, actonitrril, tri ‎chloromethane, dichloromethane, water, tolune, bezene, hexane, dimethyl sulphoxide extracts suggest that ‎maximum antibacterial activity was  found for ethanol, methanol, ethyl acetate and dimethyl sulphoxide ‎extracts. Where as high antifungal inhibition observed for ethanol, acetone, acetonitril extracts‎‎.



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specialty journal of biological sciences
Issue 1, Volume 6, 2020