TY  - JOUR
T1  - Role of Mutations in Increasing Protein Constancy
A1  - Ali Ramezani Ahmadabadi
A1  - Kaveh Mohammadi
A1  - Milad Valitabar
JF  - specialty journal of chemistry
JO  - SPEC. J. CHEM.
SN  - 2521-3164
Y1  - 2018
VL  - 3
IS  - 1
SP  - 1
EP  - 9
N2  - There are many methods to choose mutations that increase the constancy of proteins, including rational design, functional screening of accidentally generated mutant libraries, and comparison of naturally occurring similar proteins. The protein engineer’s toolbox is expanding and the number of successful instances of engineered protein constancy is increasing. Still, the selection of heat constancy mutations is not a standard process. Selection is complicated by lack of knowledge of the process that turns into thermal inactivation and by the fact that proteins employ a large variety of structural tricks to get constancy.
UR  - https://sciarena.com/article/role-of-mutations-in-increasing-protein-constancy
ER  -