The Effects of Curcumin on Plasma Levels Cytokines, on Endurance-Trained Athletes
Omid Salehian, Golrokh Mohammadi, Naser Amiri
The purpose of this study was to determinate the effects of natural curcumin supplementation on Levels of plasma cytokines during 8 weeks of long-term intensity treadmill training in endurance-trained athletes. 20 male endurance-trained athletes (age 20 years, weight 75 kg) participated in this study. The participants were randomly assigned to exercise supplement (E+S, n=8), and exercise (E, n=8) groups. All subjects participated in 8 weeks of long-term intensive treadmill training. Venous blood samples were collected immediately after exercise (T1),1 hour after exercise (T2), 24 hours after exercise (T3). In the E group 8 weeks of training increased the seminal, IL-6, tumor necrosis factor (TNF)- immediately after exercise (T1) ,1 h after exercise (T2),24 hours after exercise (T3) (P<0.05) and but E+S group showed decrease significantly in levels of TNF and IL6 and increased significantly in IL10 immediately after exercise (T1) ,1 h after exercise (T2),24 hours after exercise (T3) p<0.05. It may be possible that intake curcumin supplementation lead to decrease inflammatory cytokine such as IL6 and TNF and increase anti inflammatory cytokine such as IL10.